With freezing temperatures, seas of liquid methane and toxic atmosphere devoid of any liquid water, it may seem unlikely that Titan could give rise to life.
But in such environments, it may be possible for there to be methane-based, oxygen-free extraterrestrial life, according to researchers at Cornell University.
On Titan, temperatures of minus 180 degrees Celsius would make it difficult for processes like metabolism and reproduction to occur.
But the theorised cell membrane, which houses the cell's organic matter, is composed of nitrogen instead of water, allowing it to do just that, 'SPACE.Com' reported.
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But plenty of exoplanets (and even solar system moons) exist well outside this range, where liquid water can't exist.
Researchers in the study were able to model a cell that supports metabolism and reproduction but that's constructed from nitrogen, carbon and hydrogen-based molecules - all of which are known to exist within Titan's frigid seas.
Like a lipid bilayer membrane here on Earth, it's both rigid and flexible, controlling the transportation of materials in and out of the cell.
"Ours is the first concrete blueprint of life not as we know it," Stevenson said.
The next step will be to demonstrate in the laboratory how such membranes function in a methane environment. In the long run, scientists might also be able to model possible observable indicators of alien life.
If life does exist on Titan, it would demonstrate that methane, in addition to water, could be an indicator of life, and that life could more easily populate the cosmos.
The findings were published in the journal Science Advances.