Ghosal produced a 76-minute epic battle against Egyptian sixth seed Karim Abdel Gawad before going down 9-11, 3-11, 11-8, 11-5, 9-11 in the quarterfinal match.
Earlier, Ghosal, who dropped out of the top 20 as per the latest PSA rankings, made a bright start against fourth seeded Colombian Miguel Rodriguez in the opening round.
The Indian produced a grand come back to convert a 1-2 deficit to a 3-2 win, in the first round match that lasted 90 minutes. That 11-9, 8-11, 8-11, 11-9, 11-5 win helped Ghosal get a place in the quarterfinal.
Dipika, who had to come into the main draw via the qualification phase, lost 5-11, 5-11, 6-11 in the first round against Hong Kong Open winner Nouran Gohar of Egypt, seeded third.
However, Joshna, who has just returned to the top-10 ranking in the world, survived some tense moments to beat qualifier Heba El Torky of Egypt in four games 8-11, 11-8, 11-4, 11-7. But in the quarterfinal, she lost 7-11, 5-11, 6-11 to top seed Laura Massaro of England.