Saint Nicholas was a 4th Century bishop who liked to give gifts secretly.
An image of the saint was produced using a facial reconstruction system and 3D interactive technology by Liverpool John Moores University's Face Lab, BBC News reported.
Professor Caroline Wilkinson said the image was based on "all the skeletal and historical material" available.
The saint was believed to have left secret gifts, such as putting coins in shoes that were left out for him, leading him to be the model for Father Christmas.
It also includes Saint Nicholas' severely broken nose, which she said had "healed asymmetrically, giving him a characteristic nose and rugged facial appearance".
The saint, who died in 343 AD, was the Greek bishop of Myra. The town, now known as Demre, lies on the southern coast of Turkey.