The "Bridge of Spies" actor will play the role of deputy director of the CIA.
Paul Greengrass, who directed 2007's "The Bourne Ultimatum", will helm the project.
He will also co-write the script with Christopher Rouse.
Alicia Vikander, Tommy Lee Jones, Vincent Cassel, Viggo Mortensen are also starring in the project.
The production of the film has already started in Budapest.
The movie is scheduled for July, 2016 release.