With the Syrian regime suspected of using chemical agents against rebels, US and Western military officials are planning for a possible worst-case scenario in which an international force would move in to neutralise the lethal weapons.
Any attempt to seize control of chemical agents in Syria would depend on the intelligence gathered by foreign spy services, which have struggled at times to track the Damascus regime's stockpiles.
"The first thing is you have to know where they are... And where are the production sites and production-related sites?" said David Kay, the former UN weapons inspector who led the Iraq Study Group.
Syria is believed to have hundreds of tons of chemical agents such as sarin and VX as well as mustard gas, but the precise details of its arsenal remain unknown.
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To take control of the weapons, the US or its allies would have to send in boots on the ground, including teams of technical experts, special forces units and a large contingent - likely tens of thousands - of conventional troops to seize and guard chemical sites, analysts said.
The intervention force would also need to destroy missiles, aerial bombs and artillery shells used to deliver chemical agents, which would likely require a wave of air strikes.
Part of the arsenal could be "entombed" by bombing which destroys and seal bunkers with rubble, Eisenstadt said.
The US military has a bomb, the BLU-119/B, specifically designed to incinerate chemical agents, though the Pentagon has never disclosed how it has fared in tests.