DuVernay, 42, said she did meet with executives about bringing the story of first Black superhero but they had different ideas of how to move forward, reported Entertainment Weekly.
"I guess I'll declare my independence from this rumour on 4th of July weekend and Essence weekend!" she said the Essence festival in New Orleans.
"I'm not signing on to direct Black Panther. I think I'll just say we had different ideas about what the story would be. Marvel has a certain way of doing things and I think they're fantastic and a lot of people love what they do. I loved that they reached out to me."
"I loved meeting Chadwick and writers and all the Marvel execs," said DuVernay.
"In the end, it comes down to story and perspective. And we just didn't see eye to eye. Better for me to realise that now than cite creative differences later," she said.