Second seeded Vishnu Vardhan, fourth seeded Jeevan Nedunchezhiyan and fifth seed Ranjeet Virali Murugesan also booked their places in the semi-finals.
In the quarterfinal match, Ashwin was in the driver's seat leading 6-1 in the first set tie-break, but Ti-Chen fought back to take the set 9-7.
In the second, Ashwin seemed to be low on moral and made quite a few unforced errors as Ti-Chen, with two breaks (third and ninth game), sealed the set and match.
In another quarterfinal, Vishnu Vardhan was in his elements and overpowered his rival N Sriram Balaji with his booming first serve and strong forehand returns.
Vishnu blasted as many as 10 aces in the tie while Balaji was struggling to hold his serve making four double faults.
In the first set Balaji began with a double fault and dropped the first game, slamming a double handed backhand out and Vishnu, who fired three aces, took the second game for a 2-0 lead. He never looked backed as he raced to a 6-0 win, breaking Balaji again in the third and fifth games.
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Though Balaji played much better in the second set, Vardhan, who broke him in the second game, went on to wrap the set 6-4.
Virali Murugesan defeated third seed Vijayant Malik 6-2 6-3 while Nedunchezhiyan thumped Thai challenger Warit Sornbutnark 6-1 6-2.
In the semifinals, Nedunchezhiyan meets Ti-Chen while Virali Murugesan takes on Vishnu Vardhan.
In the doubles, the top seeded pair of Arun Prakash Rajagopalan and N Sriram Balaji is in line for its third successive title after entering the final by beating the duo of Abhijeet Tiwari and Ashwin Vijayragavan 5-7 6-2 10-8.
They meet Nedunchezhiyan and Virali Murugesan who defeated Vijayant Malik and Kaza Vinayak Sharma 6-4 6-4 in the other semifinal.