He followed up his first round 65 with a 66, that included a back nine with five birdies against no bogeys.
At 11-under, he was two shots ahead of reigning Masters champion, Sergio Garcia, 2017 PGA Tour Rookie of the Year Xander Schauffele and Spaniard Rafa Cabrera Bello.
Overnight leader Louis Oosthuizen (71), World No. 1 and defending champion Dustin Johnson (66), two-time Masters champion, Bubba Watson (66), fellow Asian Kiradech Aphinbarnrat (69) were among those Tied-5th and four behind Sharma.
I'm really happy. I couldn't be in a better situation. Played so well, and the bogeys that I made today were just three putts. Otherwise I just got the ball in play all day and it was great to finish with three birdies in a row, said Sharma.
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I thought about nothing, I just wanted to have fun. It's my first WGC and I was happy that I'll play four days because I missed the cut in the last two events that I played. Even though I missed the cuts, I knew I was playing well."
He moved into sole lead at that stage, but back-to-back three-putts on the next two holes saw him slip back to overnight six-under.
Not allowing the situation or the stage to get to him, he steadied the ship and parred the next six holes till he reached the turn. His birdie run on the back nine started on 11th, when he reached the green in two at par-5 11th and birdied from under 10 feet. Another birdie, this time from 24 feet on Par-4 12th saw him move further up.
I worked all my life to come and play at a high stage like this. You have to expect great things from yourself if you want to play at a high stage, said Sharma.
Sharma wants to keep his foot on the pedal as a strong week could open new doors and see him catapult into the top-50. It could also earn him spots at WGC-Dell Technologies Match Play, Masters Tournament and THE PLAYERS Championship in the coming weeks.
This is Sharmas WGC debut and he has not played at any Majors, though a spot at the Open is booked with his win in Joburg.
The last player to win on his PGA TOUR debut was Jim Benepe at the 1988 Beatrice Western Open.
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