The 30-share index, which had gained 415.78 points in the previous two sessions, fell 132.37 points, or 0.50 per cent, to 26,494.09 in early trade today.
Stocks of FMCG, teck, IT and auto were major losers, dragging the key indices down.
Bucking the trend were stocks of realty companies, which were in demand after Prime Minister Narendra Modi on December 31 announced that loans of up to Rs 9 lakh taken in the new year under the new scheme of Pradhan Mantri Awas Yojana will receive interest subvention of 4 per cent and loan of up to Rs 12 lakh will get a 3 per cent interest waiver.
The broad-based NSE Nifty was down 44.80 points, or 0.54 per cent, to 8,141.
Brokers said that profit-booking in stocks that logged gains recently, and absence of cues from other global markets which are closed today, left an impact on the markets.