Snapping three days of gains, the Sensex fell by 160.13 points, or 0.81 per cent, to 19,575.64. The index had gained 449 points in the last three sessions.
Similarly, the Broad-based National Stock Exchange index Nifty fell by 55.35 points, or 0.92 per cent to 5,944 points after touching a low of 5,930.15.
The Reserve Bank today cut the key interest rate by just 0.25 per cent to 7.25 per cent and kept the liquidity enhancing cash reserve requirement unchanged, disappointing the industry and stock market.
"While RBI did cut policy rates by 25 basis points as expected, it has adopted an unexpectedly hawkish stance despite mounting evidence for easing inflation going ahead and still soft economic activity," said MOFSL Chairman and Manging Director Motilal Oswal.
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The banking sector index suffered the most by losing 2.40 per cent to 14,183.60 as ICICI Bank, SBI, HDFC Bank and Housing Development Finance Corp suffered heavy losses on profit-booking.
The realty sector fell by 1.39 per cent to 1,902.66, and consumer durable index by 1.06 per cent to 7,421.56.
In 30-BSE index components, 18 stocks declined led by GAIL India, Cipla, ITC, ONGC and TCS.
However, a gain in Infosys, Sterlite Industries, Hindalco, Jindal Steel, RIL , Sun Pharma and L&T, saved the market from any major fall.