The index fell on selling in FMCG, PSU, metal and realty stocks, while weak Asian cues amid mixed European openings also weighed on market sentiment.
The 30-share Sensex initially touched a high of 19,751.03 and then declined on weak Asian trends to settle at 19,593.28, a fall of 154.91 points or 0.78 per cent. That was the lowest close since 19,294.12 on July 10.
The National Stock Exchange's Nifty index fell 54.55 points, or 0.93 per cent, to 5,831.65. The SX40 index on the MCX-SX closed at 11,695.58, down 0.81 per cent.
Fast moving consumer goods giants ITC and Hindustan Unilever, which posted Q1 earnings last week, declined after their recent rally and together contributed almost 100 points to the Sensex fall.
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HDFC Bank, Dr Reddy's Laboratories, ONGC, Bharti Airtel, Reliance Industries, SBI, Coal India, Hindalco, Bajaj Auto, Sterlite Industries, Maruti Suzuki and Tata Steel also closed with losses.
The RBI's First Quarter Review of Monetary Policy is scheduled tomorrow. Besides, the US Federal Reserve's two-day meet on July 30 and 31 on policy led operators and investors to tread cautiously.