The rupee's weakness against the dollar too dampened the overall mood.
The 30-share index fell 100.07 points, or 0.30 per cent, to 32,702.37, with sectoral indices of banking, auto, metal and PSU trading dropping up to 1.76 per cent.
The gauge had lost 67.28 points in the previous session.
The NSE Nifty too shed 39.15 points, or 0.38 per cent, at 10,079.10.
Brokers said sentiment remained somewhat subdued as investors kept their positions at a low ebb amid expectation that the central bank may keep rates unchanged.
Among the Asian bourses, Hong Kong's Hang Seng was down 1.12 per cent while Japan's Nikkei shed 0.90 per cent. Shanghai Composite Index too fell 0.61 per cent in early trade today.
The US Dow Jones Industrial Average ended 0.45 per cent lower yesterday.
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