The NSE Nifty fell below the 8,500-mark to trade at 8,498.65 points, down by 30.80 points, or 0.36 per cent over previous close.
The 30-share Sensex fell further by 109.20 points, or 0.38 per cent, to 28,072.94 with IT, metal, teck, banking, capital goods and power stocks leading the fall.
The gauge lost 281.17 points in the previous two consecutive sessions.
Brokers said investors indulged in selling after a weak trend at other Asian markets following overnight sell-off at the US markets on corporate earnings concern.
In other Asian markets, Hong Kong's Hang Seng index was down 0.53 per cent while Japan's Nikkei shed 1.25 per cent in early trade today.
The US Dow Jones sank 1 per cent yesterday.