After a better start at 19,673.16, the Sensex fell by 142.88 points, or 0.73 per cent to settle at 19,427.56. The gauge had gained 208 points in the previous session after a three-day string of losses.
The broad-based National Stock Exchange index Nifty fell by 36.35 points, or 0.62 per cent to end at 5,872.60, after touching the day's high of 5,945.65.
ICICI Bank and HDFC Bank were among top losers in 30-share Sensex. Axis Bank ended nearly 1 per cent lower.
"Banking stocks pared their recent gains after news of RBI probing the money-laundering practices in the said banks weakened investor sentiment," said Rakesh Goyal, Senior Vice President, Bonanza Portfolio Ltd.
Also Read
While Asian stocks were mixed, a lower opening in Europe as eurozone leaders eased constraints on national budgets amid a deepening recession, further influenced the Indian markets.
ICICI Bank ended 3.93 per cent lower, HDFC Bank by 1.67 per cent. The negative sentiment hit others including Yes Bank and Indusind Bank.