The 30-share index which had lost 400.81 points in the previous three sessions, moved further down by 163.25 points, or 0.78 per cent, to 20,872.36 with banking, capital goods, realty, oil and gas and power sector stocks retreating.
The wide-based National Stock Exchange index Nifty fell 51.80 points, or 0.83 per cent, to 6,185.25.
Brokers said sentiments turned distinctly weak as Industrial production entered the negative territory after three months, contracting by 1.8 per cent in October mainly due to poor performance of the manufacturing sector and retail inflation climbing to a nine-month high of 11.24 per cent in November.
The US Dow Jones Industrial Average ended 0.66 per cent down in yesterday's trade.