Besides, a cautious approach adopted by participants ahead of wholesale inflation data for May to be released later in the day, also influenced the sentiments.
Stocks of realty, metals, capital goods, consumer durables, PSUs, oil & gas and banking sectors led the fall.
The 30-share Sensex fell by 34.29 points, or 0.14 per cent, to trade at 25,193.88. It had lost 348.04 points in the previous session on Friday.
Apart from profit-booking by retail investors, a weakening trend in the Asian region on worries over escalating violence in Iraq, dampened the trading sentiments here, brokers said.
Among other Asian markets, Hong Kong's Hang Seng fell by 0.07 per cent, while Japan's Nikkei shed 0.62 per cent in early trade today.
The US Dow Jones Industrial Average ended 0.25 per cent higher in Friday's trade.