The 30-share barometer, which had gained over 56 points in the previous session, fell by 84.84 points, or 0.48 per cent, to 17,356.03. All the sectoral indices were trading in the negative zone, with losses up to 0.90 per cent.
Similarly, the wide-based National Stock Exchange index Nifty shed 30.15, or 0.57 per cent, to 5,243.85.
Brokers said apart from profit-booking by funds and retail investors, a weak trend in the Asian region following overnight losses in Europe and on the Wall Street after a third straight monthly contraction in US manufacturing activity, mainly dampened the trading sentiment here.
In the Asian region, Hong Kong's Hang Seng fell 1.06 per cent, while Japan's Nikkei shed 0.72 per cent in early trade today.
The US Dow Jones Industrial Average ended 0.42 per cent lower in yesterday's trade.