The 30-share index fell by 85.12 points or 0.25 per cent to 33,639.32 in early trading. The gauge had garnered 964 points in the previous eight sessions.
The broader Nifty of NSE dropped by 17.30 points or 0.17 per cent to 10,382.25.
Apart from profit booking by participants in recent gainers, sustained foreign fund outflows dampened the sentiment, brokers said.
NTPC, ONGC, Power Grid, ICICI Bank, ITC Ltd, L&T, Dr Reddy's, Reliance Industries, Bharti Airtel, Infosys, SBI and Coal India fell up to 1.67 per cent.
In the Asian region, Japan's Nikkei rose 0.17 per cent, while Shanghai Composite Index shed 0.49 per cent and Hong Kong's Hang fell 0.65 per cent in early deals.
The US Dow Jones Industrial Average ended 0.10 per cent higher yesterday.