The 30-share index resumed lower at 21,797.61 and hovered in a range of 21,812.46 and 21,746.42 before quoting at 21,793.00 at 1000hrs, showing a loss of 39.86 points or 0.18 per cent from its last close.
The NSE 50-share Nifty also moved down by 14.35 points or 0.22 per cent to 6,509.70 at 1000hrs.
However, Wipro firmed up by 1.65 per cent followed by Bharti Airtel 1.15 per cent and TCS 0.68 per cent.
Asian stocks fell in their early trade after the Federal Reserve signalled a faster timetable for raising rates. Key benchmark indices in Hong Kong, China, Taiwan, Singapore, South Korea, Indonesia and Japan were down 0.25 per cent to 1.33 per cent.
US stocks slipped on Wednesday as the Federal Reserve's latest policy statement raised jitters about the prospect of interest rates rising sooner than anticipated.