The Sensex closed 123.91 points lower, or 0.65 per cent, to 18,884.19, a level seen on March 1. The index had lost over 562 points in last three sessions.
Similarly, the broad-based National Stock Exchange index Nifty fell below 5,700 level, by losing 51.55 points, or 0.90 per cent, to 5,694.40.
Brokers said market sentiment turned bearish after the DMK withdrew support to the Congress-led UPA government on Sri Lankan Tamil issue and raised fears of halt in the ongoing economic reforms.
The current downfall was led by stocks of financial and interest-sensitive stocks like realty and banking sectors.
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Shares of Housing Development and Infrastructure plunged by 19.90 per cent to Rs 48.70 after credit agency Credit Analysis and Research downgraded the company's non-convertible debentures issue.
State Bank of India dropped by 3.87 per cent to Rs 2,117.75, ICICI Bank by 2.85 per cent to Rs 1,001.60, HDFC Bank by 0.78 per cent to Rs 4.90, Axis Bank by 1.65 per cent to Rs 1,300.30 and Yes Bank by 1.72 per cent to Rs 431.50.
Bucking the weak trend, the stocks of Infosys, Tata Consultancy Services, Cipla, Dr Ready, Hero MotoCorp, Hindustan Uniliver and ITC gained and capped the losses to some extent.