The BSE 30-share barometer declined by 60.39 points, or 0.21 per cent, to 27,721.86 with teck, realty, IT, healthare, capital goods and power were trading in negative zone, falling up to 0.90 per cent. It had lost 274.69 points in the previous two sessions.
Also, the NSE Nifty was trading down by 11.10 points, or 0.13 per cent, at 8,561.45.
Brokers said that apart from continuous selling by investors, a mixed trend at other Asian markets with US Fed chief Janet Yellen suggesting that interest rates could be raised this year also added to the weakening sentiment.
The US Dow Jones Industrial Average ended 0.29 per cent lower in Friday's trade.