The 30-share index, which had gained over 684 points in the past four sessions, fell by 95.38 points, or 0.57 per cent, to 16,553.67 with stocks of consumer durables, oil and gas and capital goods sectors succumbing to profit-booking.
Similarly, the wide-based National Stock Exchange index Nifty declined by 31.90 points, or 0.63 per cent, to 5,017.75.
Brokers said besides profit-booking by speculators after recent gains and a weak trend on other Asian bourses, US Federal Reserve Chairman Ben Bernanke denting stimulus hopes, mainly influenced the trading sentiment here.
In the Asian region, Hong Kong's Hang Seng index fell by 0.17 per cent, while Japan's Nikkei Index by 0.60 per cent in the morning trade today.