Optimism generated after the US averted the debt crisis for a few months was tempered by the World Bank's sharply lower growth estimate of 4.7 per cent for the Indian economy.
TCS, Infosys and Wipro were among the shares that dragged the Sensex lower on profit booking, while heavyweights ITC, Reliance Industries and ONGC supported it.
TCS had gained 15 per cent between September 30 and October 15, while Infosys rose 11 per cent in this period. Both companies advanced in the run-up to their second-quarter earnings.
The S&P BSE Sensex, which fell for the second day, opened at 20,579.56, higher than the previous close. After touching 20,629.80, the index dropped to 20,375.42 before ending at 20,415.51, down 132.11 points or 0.64 per cent.
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"Global cues were positive as US finally signed a deal to end government shutdown and thus tensions were released," said Nidhi Saraswat, Senior Research Analyst at Bonanza Portfolio Ltd. "However, profit booking led to selling pressure today."
Overseas investors bought a net Rs 1,136.23 crore of shares on October 15, according to provisional data on the stock exchanges.
Bajaj Auto shares gained 1.92 per cent after reporting a 13 per cent increase in profit for the second quarter ended September 30.