The 30-share barometer, which had gained 50.83 points in yesterday's volatile session, fell by 71.28 points, or 0.41 per cent, to 17,470.36.
Stocks of IT, power and realty sectors lead the fall.
Similarly, the wide-based National Stock Exchange index Nifty shed 29.15 points, or 0.55 per cent, to 5,285.90.
Marketmen said selling by funds and retail investors ahead of first quarter GDP data to be announced later in the day today amid a subdued trend in Asian markets, following weak Japanese economic figures, mainly influenced the trading sentiment here.
In Asian region, Hong Kong's Hang Seng index was down by 0.25 per cent, while Japan's Nikkei Index lost 1.11 per cent in the morning trade today.
The US Dow Jones Industrial Average had ended 0.81 per cent lower in yesterday's trade.