The 30-share Sensex resumed higher at 18,455.80 and showed signs of firming up only to decline afterwards. It settled at 18,437.78, recording a modest loss of 12.45 points or 0.07 per cent from its last weekend's level. The index has now lost 603.17 points or 3.17 per cent in four sessions.
Similarly, the NSE 50-share index Nifty also moved down by 10.30 points or 0.19 per cent to end at 5,542.95.
Among Sensex gainers, Bhel closed 2.6 per cent up on rising order inflows. Shares of Bharti Airtel gained 3.90 per cent to end at Rs 281.20 after the Supreme Court allowed 3G roaming pacts to continue till next date of hearing.
Overall, 13 Sensex stocks declined including SBI, ICICI Bank, HDFC, L&T, Jindal Steel and Sterlite Industries.
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The IT sectoral index suffered the most by losing 0.98 per cent to 6,664.93 points after Infosys fell 1.07 per cent to ahead of Friday earnings. TCS and Wipro also ended lower.
Asian stocks, barring Japan, dropped after reports said China saw more infections from a deadly new strain of bird flu. Key benchmark indices in China, Hong Kong, Singapore, Taiwan and South Korea fell up to 2.39 per cent. However, Japan's Nikkei Average rose 2.80 per cent.