State Bank of India, the country's largest lender, HDFC Bank and ICICI Bank were among the shares that dragged the Sensex lower. The fall would have been more pronounced but for gains in HDFC, Larsen & Toubro and Reliance Industries shares.
Sectors that fell were FMCG, realty, metals and banks.
Cigarette major ITC tumbled 3.63 per cent and was the top loser on the Sensex after CLSA cut its earnings per share estimates by around 2 per cent.
The 50-share CNX Nifty on the National Stock Exchange dropped 43.80 points, or 0.71 per cent, to end at 6,101.10. The SX40 index of the MCX Stock Exchange closed almost 60 points down at 12,249.69.
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"Nifty opened on a flat note and witnessed selling pressure for rest of the trading day. Intraday volatility was seen ahead of the RBI's monetary meet tomorrow and also as FO expiry day is approaching this week," said Nidhi Saraswat, Senior Research Analyst at Bonanza Portfolio Ltd. "Further, profit-booking aggravated the selling sentiment."
In September, RBI Governor Raghuram Rajan surprised the markets by increasing the repo rate by 0.25 per cent in a bid to check inflation.
The market may also remain volatile as investors in the futures and options segment decide whether to roll over their positions on the expiry of equity derivative contracts on Thursday, a broker said.