Besides, a widening trade deficit to 18-month high in September influenced market sentiments.
The 30-share barometer, which had lost 34.74 points in the previous session on Tuesday, lost another 100.86 points, or 0.38 per cent, to 26,248.47 with metal, oil & gas, capital goods, power and consumer durables sectors, leading the fall.
Markets remained closed yesterday on account of Assembly elections in Maharashtra.
Similarly, the National Stock Exchange index Nifty fell by 27.55 points, or 0.35 per cent, to 7,836.45.
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Meanwhile, India's exports grew marginally by 2.73 per cent in September, but a surge in gold imports pushed the trade deficit to about 18-months high of USD 14.2 billion.
Among other Asian markets, Japan's Nikkei was down 2.35 per cent, while Hong Kong's Hang Seng shed 0.98 per cent in early trade.
The US Dow Jones Industrial Average ended 1.06 per cent down in yesterday's trade.