The National Stock Exchange's broad-based index Nifty also closed at record high of 6,601.40 points, up by 11.65 points over the last close.
Both the indices surged to new record intra-day high levels. The Sensex touched the peak of 22,172.20 points while Nifty rose to 6,627.45 points in day trade.
After initial surge, markets rolled back to minimise the day's gains on profit booking and investors squaring up their pending positions ahead of monthly settlement in the derivatives segment tomorrow.
A firming global trend after the US consumer confidence climbed to a six-year high further supported the uptrend.
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In 30-BSE index components, 16 stocks climbed.
Gains in Larsen & Toubro, Reliance Industries (RIL) and Tata Motors helped the Sensex post gains for the third straight day.
Maruti Suzuki, Bajaj Auto, Axis Bank, Bharti Airtel, ONGC and Coal India were among other major gainers.
The metal sector index gained the most by surging 2.70 per cent to 9,541.42, followed by capital goods index by 1.35 per cent to 11,893.28.