Meanwhile, NSE Nifty fell for the first time in eight days to end at 8,750.20, down 83.80 points.
A cautious stance adopted by investors ahead of the fourth quarter earnings by several bluechip companies amid mixed global cues led to the fall in domestic markets, brokers said.
The 30-share BSE index resumed higher at 29,087.25 against last close of 29,044.44 points. The barometer firmed up further to the day's high of 29,094.61 on the back of easing retail inflation.
Of 30-Sensex kitty, 23 stocks ended lower, while 7 other finished higher.
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The 50-issue Nifty slipped below 8,800-level by falling 83.80 points or 0.95 per cent to close at 8,750.20. Intraday, it hovered between 8,840.80 and 8,722.40.
Investors, who had been accumulating stocks from previous several sessions, turned cautious ahead of earnings from bluechips such as TCS, Infosys and RIL and indulged in offloading their positions by booking profits, brokers said.
Meanwhile, continuing the deflationary trend for fifth month in a row, inflation touched a record low of (-)2.33 per cent in March on cheaper manufactured goods and food items.
The BSE midcap index ended in negative zone with a fall of 0.51 per cent while smallcap index ended 0.34 per cent down.
Meanwhile, a mixed trend was seen other Asian markets, while European markets were trading higher in its morning session.
Sectorwise, BSE healthcare index suffered the most by falling 1.55 per cent, followed by infra at 1.54 per cent, auto (1.49 pc), IT (1.46 pc), realty (1.37 pc), power (1.29 pc), capital goods (0.96 pc), metal (0.58 pc), bankex (0.32 pc) and consumer durables (0.24 pc).