TCS, Reliance Industries, Wipro and Infosys were the biggest drag on the index. Coal India, Jindal Steel and BHEL were among the major losers as 19 shares on the Sensex declined.
Among the sectoral indices, IT, power, realty and metal retreated.
The 30-share S&P BSE Sensex opened little changed and surged to 21,039.42, crossing the 21K mark after 35 months on buying in auto, banking, consumer durables and oil and gas sectors on the back of persistent foreign capital inflows.
"IT is in correction mode for short term but will ultimately outperform if one has view of more than 3-6 months," said Rakesh Tarway, AVP Research, Motilal Oswal Securities. "There will be some buying in beaten down sectors of infra, banking. Apart from this, media will do well."
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The CNX Nifty on the National Stock Exchange moved down 14 points, or 0.23 per cent, to 6,164.35. The SX40 on the MCX Stock Exchange closed at 12,331.32, down 7.5 points.
Shares of PSU banks gained after the Ministry of Finance said after trading hours yesterday that the government has approved infusion of Rs 14,000 crore in 20 lenders.
Overseas investors pumped in a net Rs 644.80 crore in shares yesterday, according to preliminary data from the stock exchanges.
Most Asian markets ended higher after a measure of Chinese manufacturing hit a seven-month high. Key indices in South Korea, Singapore, Taiwan and Japan rose while indices in China and Hong Kong fell.