Domestic shares logged their third weekly fall in a row as the Sensex lost 654.71 points or 2.49 per cent and Nifty dropped 192.05 points or 2.41 per cent during the week.
The short trading week ended on a negative note as two macroeconomic data stoked fears that Indian economy is still not out of the woods.
Industrial production slackened to a four-month low of 3.6 per cent while retail inflation inched up to 5 per cent, government data showed yesterday.
"Bears continue to tighten grip in line with poor global cues, and markets thereby, fell on fears of a rate hike by Fed next month," said Gaurav Jain Director Hem Securities.
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The BSE Sensex stayed in the negative zone through out the day and touched a low of 25,540.73 before winding up 256.42 points or 0.99 per cent down at 25,610.53, its weakest closing since September 11.
The 50-issue NSE Nifty cracked below the 7,800-mark by plunging 62.75 points or 0.80 per cent to close at 7,762.25. Intra-day, it hovered between 7,730.90 and 7,775.10.
Stock exchanges were closed yesterday on account of "Diwali Balipratipada".
In individual stocks, Vedanta suffered the most on Sensex by falling 4.23 per cent followed by Cipla at 3.76 per cent.
On the other side of spectrum, shares of Coal India emerged top gainers among Sensex constituents by climbing 2.60 per cent, followed by Bharti Airtel 0.89 per cent.
Key indices in China, Hong Kong, Japan, Singpaore, South Korea and Taiwan dropped by 0.51 per cent to 2.15 per cent.
European markets were also lower as the key indexes in Germany, France and the UK were down in the range 0.11 per cent to 0.46 per cent.