In contrast, broader markets were in a better shape with the mid-cap and small-cap indices closing higher by 1.10 per cent and 0.39 per cent, respectively.
Falling for a second straight session, ICICI Bank emerged as the top Sensex loser, skidding 4.08 per cent to close at Rs 226.95 as the company posted its worst numbers in over a decade with net profit plunging 87 per cent in March quarter.
Markets in China, Hong Kong, Malaysian, Singapore and Thailand remained closed for public holidays.
Housing finance major HDFC Ltd, however, perked up by 0.36 per cent on 30.76 per cent surge in consolidated net profit to Rs 3,460.46 crore for the March quarter.
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"Value buying efforts were capped by India's PMI figures released during the day, which showed manufacturing activity slowed sharply in April," Anand James Chief Market Strategist Geojit BNP Paribas Financial Services.
The 30-share index stayed in the negative zone throughout the day and settled 169.65 points or 0.66 per cent lower at 25,436.97 after touching a low of 25,341.14. This is the weakest closing since April 12.
The broader Nifty also succumbed to selling and slipped below the 7,800-mark in early trade to hit a low of 7,777.30 before recovering partially to close 43.90 points or 0.56 per cent down at 7,805.90.
On the other side of the spectrum, the country's largest carmaker Maruti Suzuki ended 0.91 per cent up at Rs 3,829.55 after it posted a 13.3 per cent growth in sales in April.
Back home, out of the 30-share Sensex, 18 scrips ended
lower.
Major losers were, ICICI Bank (4.08 pc), Dr Reddy's (2.66 pc), Adani Ports (1.93 pc), Bharti Airtel (1.64 pc), HDFC Bank (1.37 pc), SBI (1.35 pc), ITC (1.20 pc), Tata Steel (1.07 pc), Wipro (0.98 pc) and Infosys (0.84 pc).
However, BHEL rose by 1.91 per cent followed by GAIL (1.89 pc) Hero MotoCorp (0.99 pc) and Maruti (0.91 pc).
While, consumer durables rose 1.07 per cent, metal 1.02 per cent and energy 0.26 per cent.
The market breadth was negative as 1,327 shares ended lower, 1,283 closed higher while, 118 ruled steady.
The total turnover fell to Rs 2,425.66 crore from Rs 2,817.96 crore on Friday.