The 30-share index resumed lower at 30,553.89 and hovered in a range of 30,610.84 and 30,316.92 before settling at 30,365.25, showing a loss of 205.72 points, or 0.67 per cent.
The gauge had gained 136.18 points in the previous two sessions.
The NSE 50-share Nifty also tumbled 52.10 points or 0.55 per cent to 9,386.15, after shuttling between 9,448.05 and 9,370.
At least 22 people, including children, were killed and 59 others injured when a suicide bomber blew himself up as thousands of fans were exiting a pop concert in Manchester -- the deadliest terror attack in the UK since the 7/7 bombings of 2005.