The 30-share index was 70.92 points or 0.26 per cent lower at 26,963.58 in early trade with sectoral indices led by IT, healthcare, banking and capital goods, trading in the negative zone, falling by up to 0.78 per cent.
The gauge had lost 274.10 points in the previous session on Friday.
The National Stock Exchange Nifty too dropped by 22.15 points, or 0.26 per cent, to 8,327.20.
Among other Asian markets, Hong Kong's Hang Seng was down 0.03 per cent and Japan's Nikkei fell 1.06 per cent in early deals. China's Shanghai Composite index too fell 0.47 per cent.
The US Dow Jones Industrial Average had ended 0.48 per cent higher in Friday's trade.