Also, a weak trend in other Asian markets after a key advocate for free trade in the White House announced his resignation, fanning fears that President Donald Trump would go ahead with import tariff hike and risk a trade war, weighed on the sentiment, brokers said.
The BSE 30-share index slipped by 132.83 points, or 0.39 per cent, to 33,184.37. The benchmark had lost 1,128.55 points in the previous five sessions.
Major laggards were ICICI Bank, Adani Ports, SBI, Hero Motocorp, Sun Pharma and Tata Steel.
Also, NSE Nifty was trading down by 50.60 points, or 0.49 per cent, at 10,198.65.
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Meanwhile, on a net basis, domestic institutional investors (DIIs) sold shares worth Rs 734.33 crore, while foreign portfolio investors (FPIs) bought shares of Rs 620.08 crore yesterday.
In the Asian region, Hong Kong's Hang Seng fell 0.04 per cent and Japan's Nikkei shed 0.19 per cent. However, Shanghai Composite Index was up 0.17 per cent in early trade.
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