Realty, Oil&Gas and Consumer Durable shares saw heavy selling on diminishing hopes of a rate cut after retail inflation marginally rose to 5 per cent in December while the country's industrial production grew 3.8 per cent in November.
The BSE Sensex resumed higher a 27,611.56 and hovered in a range of 27,670.19 and 27,324.58 before ending at 27,425.73, showing a loss of 159.54 points or 0.58 per cent.
The NSE 50-share Nify also moved down by 23.60 points, or 0.28 per cent, to 8,299.40 -- a tad below the key 8,300-mark.
Major Sensex laggards include ICICI Bank, Infosys, ONGC, HDFC and Reliance Industries while gainers include ITC, M&M and Wipro.
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Crude oil was dealt another blow Tuesday when key OPEC member the UAE said the cartel could not stop world prices plunging and called for a cut in US shale oil output.
Brent crude for February delivery fell USD 45.50 a barrel -- around its lowest point since April 2009. On Monday, it had plunged more than five percent to end below USD 50.
Global markets were mixed. In Asia, indices in China, Hong Kong and Taiwan moved up by 0.19 per cent to 0.79 per cent after data showed China's exports climbed more than estimated in December. Barometers in Japan, Singapore and South Korea eased by 0.11 per cent to 0.64 per cent.
In Europe, the UK's FTSE, France's CAC and Germany's DAX were trading higher in late morning trades.
Meanwhile, provisional data from stock exchanges showed that foreigners bought shares worth a net Rs 244.95 crore yesterday.