Serena Williams underlined her status as the Wimbledon title favourite with a 62-minute demolition of Russian qualifier Evgeniya Rodina, while Karolina Pliskova became the last top 10 seed to crash out on Monday.
Williams raced into her 13th Wimbledon quarter-final as the seven-time champion thrashed Rodina 6-2, 6-2 in a Centre Court masterclass.
Williams, who won the Wimbledon title on her last two visits in 2015 and 2016, is now on an 18-match winning streak at the All England Club.
Having missed Wimbledon last year while she prepared to have her first child in September, Serena is in pole position to win her first Grand Slam crown since becoming a mother.
On Tuesday, the 36-year-old faces Italian world number 52 Camila Giorgi, who beat Russia's Ekaterina Makarova 6-3, 6-4 to reach her first Grand Slam quarter-final. Asked if it was a flawless display, Serena admitted she is never satisfied.
"I'm a perfectionist. I always find something wrong," she said.
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"It was a good win but it was tougher than the scoreline to be honest." Giorgi, 26, had failed to get past the third round of a major since the 2013 US Open. But the 26-year-old underdog isn't ruling out an epic upset against Williams.
"I don't follow tennis, women's tennis, but I think it will be a good match," Giorgi said without a hint of a smile.
Serena's 90th Wimbledon win of her career is the most among active female players. Williams had made a tentative return to action following complications during daughter Olympia's birth, struggling in her few appearances before pulling out midway through the recent French Open with a pectoral injury.
But the 23-time major winner's blistering form and a series of shock results have paved the way for another Williams coronation at Wimbledon.
Garbine Muguruza, Maria Sharapova, Simona Halep, Petra Kvitova, Venus Williams, Caroline Wozniacki and Sloane Stephens have all been eliminated already. Kiki Bertens took care of the last of the top 10 with a 6-3, 7-6 (7/1) victory over Czech seventh seed Pliskova.
It is the first time in Wimbledon history not one of the top 10 women's seeds have reached the quarter-finals.
Bertens, who was contemplating retirement last year after losing her enthusiasm for the sport, is the first Dutch woman to reach the Wimbledon quarter-finals since Michaella Krajicek in 2007.
The 26-year-old faces German 13th seed Julia Goerges, who beat Croatian world number 55 Donna Vekic 6-3, 6-2 to seal her first Grand Slam quarter-final berth at the 42nd attempt.
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