"If I was a lady player, I'd go down every night on my knees and thank God that Roger Federer and Rafa Nadal were born, because they have carried this sport," Moore, a 69-year-old former player from South Africa told reporters at his annual state of the tournament press conference on Sunday morning.
Not surprisingly, 21-time Grand Slam champion Williams was scathing in her response.
"Obviously, I don't think any woman should be down on their knees thanking anybody like that," Williams said.
"So I don't think that is a very accurate statement. I think there is a lot of women out there who are very exciting to watch.
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"I think there are a lot of men out there who are exciting to watch. I think it definitely goes both ways. I think those remarks are very much mistaken and very, very, very inaccurate."
Williams said she quickly became aware of Moore's remarks on social media, even though she was busy Sunday morning preparing to meet Victoria Azarenka in the women's final which the Belarusian won in straight sets.
"At my morning breakfast with the media, I made comments about the WTA that were in extremely poor taste and erroneous," Moore said in a statement.
"I am truly sorry for those remarks, and apologize to all the players and WTA as a whole.
"We had a women's final today that reflects the strength of the players, especially Serena and Victoria, and the entire WTA. Again, I am truly sorry for my remarks."
But Williams said there was no mistaking their meaning.
gender-related controversy continuing to crop up in a sport that has pioneered equal compensation for women competitors -- sometimes over the objections of their male counterparts.
"Last year the women's final at the US Open sold out well before the men. I'm sorry, did Roger play in that final or Rafa or any man play in that final that was sold out before the men's final? I think not.
"I mean, you look at someone like Billie Jean King who opened so many doors for not only women's players but women's athletes in general.