The Madurai-based team led 8-0 at half-time and pumped in eight more in the second half, a press release said.
Striker R Sumithra netted six goals, including a hat-trick, Velanie Fernandes scored three, Puja Karmakar and M Nandhini scored two each while Laura Estibeiro, Manisha and A Karthika also found the net.
"This is a great start for our team and we hope to carry the momentum into our next game," coach Kalpana Dass said.
"We have been working methodically at practice. Our aim is to qualify," she added.
Sethu FC next plays J&K State Sports Councilon November 27 in what is now a five-team group following the withdrawal of Capital Complex Sporting Club.
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