The list of participants announced by FIDE, the world chess body, also includes Pentala Harikrishna, the second highest ranked Indian.
The World Cup would feature 128 players in a knock-out system. The two players who enter the final secure direct entry into the Candidates tournament in 2018 that determine who would play the current World Champion.
Interestingly, World Champion Magnus Carlsen of Norway and his challenger Sergey Karjakin are also taking part in the event.
Anand has previously won the tournament on two occasions.
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He recently tied for the second spot in the Sinquefield Cup in St Louis, USA and finished ninth in the Rapid and Blitz Chess tournament, a part of the Grand Chess tour.
The others who will be taking part in the World Cup are: Karthikeyan Murali (who qualified from Zone 3.7), Vidit Gujrathi (from Continental event 2017) and Baskaran Adhiban (FIDE nominee).
Adhiban is one of the five FIDE nominees.
As per the draw, Anand would meet Malaysian No. 1 International Master Yeoh Li Tian in the opener, while Harikrishna would meet Cuban GM Gonzalez Yuri Vidal.
In other first-round pairings, Gujrathi has been paired against Paraguayan No. 2 GM Delgado Ramirez Neuris while Adhiban would run into Vietnamese GM Nguyen Ngoc Truongson.
Sethuraman faces a tough task against GM Ruslan Ponomariov of Ukraine. If Sethuraman manages to pull off an upset, he would probably run into Harikrishna.