Addressing a conference of Pakistan's envoys here, he said such statements vitiate the atmosphere and take the two countries away from goals of regional peace and stability.
"The entire nation is dismayed by the recent irresponsible and I must say imprudent statements from the Indian political leadership. This vitiates the atmosphere and takes us further away from our goal of regional peace and stability. We will protect our vital interests at all costs," he said.
Sharif said externally-sponsored terrorism and violent extremism were grave threats to a secure and prosperous Pakistan.
He said the issue of Jammu and Kashmir cannot be relegated to the back-burner of history.
The Prime Minister pointed out that only on last Tuesday during his meeting with the UN Secretary General in Dushanbe, he urged him to play a proactive role in promoting peace in the region.