The 27-year-old actor said he had taken LSD for a drugs scene in the film in order to get an authentic performance, reported Digital Spy.
But the director Fredrik Bond said that LaBeouf did not need to take anything for the shot.
"In the script, it's Carpathian ecstasy, a special hostel ecstasy that exists in maybe just Bucharest. So, Shia said he took acid? I didn't know he went out and said that. But it was always ecstasy in the script," Bond said.
LaBeouf plays a young man who travels to Bucharest after his late mother appears in a vision.