Advocate Ali Hasnain Bukhari was on way to his office this morning when two motorcycle-riding gunmen shot him dead in Korangi area.
The gunmen shot the lawyer three times and escaped from the site after the attack.
The victim was a member of the MQM's legal aid committee and was representing several party workers in cases related to enforced disappearances and arrests.
Police said the killing could be linked to the sectarian violence which has rocked the city of over 18 million people.