The 18-year-old Sindhu fought hard for one hour and 18 minutes before losing to the two-time reigning All England champion Shixian 21-15 20-22 12-21 in the women's singles competition.
In women's doubles, Jwala and Ashwini failed to breach the defence of Luo Yu and Luo Ying, and suffered a 12-21 7-21 loss to the world number 10 Chinese pair here.
Sindhu had beaten Shixian thrice in the past but the world number two Chinese had the last laugh in the last two occasions.
"Overall, Sindhu played well. It was an extremely close and long match. She was up 20-18 but she lost two points while serving. You need a bit of luck in such close matches. Its okay, at the end of the day, you will win some and lose some. I am happy with the way she is playing," National Coach Pullela Gopichand told PTI.
In the women's doubles match, former world number 13 pair of Jwala and Ashwini suffered for their inconsistent and inaccurate strokes. The Indian duo tried to engage in long rallies with their rivals but faltered while finishing the points.