Sindhu, fresh from a bronze in Glasgow Commonwealth Games, would try to ensure that she ends up better than third, a position she managed in the previous edition which made her the first Indian to win a medal at the prestigious event.
Saina, on the other hand, is back in action after taking a break to recover from the leg injury she sustained during her Australian Open triumph in June, as a result of which she was forced out of the Commonwealth Games.
Seeded seventh, Saina has been handed a first-round bye and she will open her campaign on Tuesday against the winner of the match between New Zealand's Anna Rankin and Russia's Natalia Perminova.
Sindhu, seeded 11th, has also received a first-round bye and will start against the winner of the match between Russia's Olga Golovanova and Bulgaria's Linda Zetcheri.
Among others in the fray, Ajay Jayram will face fourth seed Kanichi Tago of Japan in his opening match, while the fast-rising K Srikanth will square off against Slovenia's Iztok Utrosa.
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