However, it was curtains for Parupalli Kashyap and B Sai Praneeth -- both of whom bowed out of the tournament after losing their second-round men's singles matches.
Olympic silver-medallist Sindhu saw off Thailand's Nitchaon Jindapol 22-20 21-17 to set up a clash with Japan's Minatsu Mitani, who won a bronze medal at the 2014 World Championships and had also defeated Saina Nehwal in the finals to clinch the 2012 French Open title.
Son Wan, seeded top, had to dig deep to end Kashyap's run. He battled for an hour and 16 minutes before getting the better of the Indian 21-16 17-21 21-16 to reach the last- eight stage.
Praneeth fought hard before going down 13-21 24-26 to seventh seeded Tzu Wei Wang of Chinese Taipei in a contest that lasted 40 minutes.
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They will next take on the third-seeded Japanese combination of Takeshi Kamura and Keigo Sonoda in the quarterfinal.
World No. 4 Sindhu, who clinched a maiden silver at Glasgow World Championship recently, had come into the match with a 1-1 record against Jindapol, who had beaten the Indian at Syed Modi International last year.
Sindhu had to battle hard in the opening game with World No. 16 Jindapol managing to grab a 9-7 and 13-10 lead but the Indian broke off at 14-16 with six straight points. The Thai shuttler drew parity before Sindhu closed the issue.
Sindhu moved ahead and grabbed a 12-9 lead and even though Jindapol managed to claw back at 15-15, Sindhu ensured that she had the last laugh.