The new ministers were sworn-in at the al-Ittihadiyah palace here, Egyptian TV reported.
The reshuffle targeted nine ministries. The new ministers of the cabinet are Galal Saeed as Minister of Transportation, Mohamed Abdel Rahem as minister of Justice, Sherif Ateya appointed as Minister of Civil Aviation, Amr el-Garhi as Minister of Finance, Dalia Khorshed appointed as Minister of Investment, Mohamed Rashed as Minister of Tourism and Khaled Ezz as Minister of Antiquities.
A new Ministry for General Business Sector was established and Ashraf el-Sharkawy was appointed as its Minister.
The Prime Minister Sherif Ismail was appointed as the head of the cabinet last September, and this is the first reshuffle to happen since his appointment.
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The changes come at a time when Egypt is facing a host of seemingly intractable problems, primarily an economy reeling from five years of unrest that has led to a severe slump in the vital tourism sector.
They also follow the recent devaluation by nearly 15 per cent of the country's weakening currency, a move that led to a surge in prices.