The acquisition expands the group's presence in the United States and builds on its purchase last summer of the US brand IT Cosmetics for USD 1.2 billion.
The cash deal will see L'Oreal acquiring the CeraVe, AcneFree and Ambi brands from the Quebec-based pharmaceutical firm in a purchase it said would nearly double the US sales of its active cosmetics division which focuses on aesthetic dermatology.
"The acquisition of CeraVe, AcneFree and Ambi strongly complement L'Oreal's brand portfolio," said Frederic Roze, president and chief executive of L'Oreal USA in a statement.
The Active division includes dermocosmetic brands such as La Roche-Posay, Vichy and SkinCeuticals.
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Founded in 2005, CeraVe offers a range of skincare products including cleansers, moisturisers and sunscreens as well as a baby line.
It is one of the fastest growing skincare brands in the US with an average growth over the past two years of over 20 percent, L'Oreal said.
Predominantly sold in the US, the brand's dynamism and its potential on the international market justified the high price paid by L'Oreal, she said.
AcneFree provides acne treatments and Ambi offers products for multicultural consumers.
The acquisition expands the firm's footprint in the United States where the demand for beauty products is flourishing: in the first nine months of 2016, L'Oreal's North American sales grew 5.4 percent compared with just 0.1 in western Europe.
The sale comes after a difficult year for the Canadian firm, which grew from a small pharmaceutical company to a global giant in the span of a decade mainly due to a growth strategy based on acquisitions.
The former Wall Street darling has come under fire for steep price hikes on drugs and is currently under investigation in the US over alleged accounts manipulation, with former senior executives being probed for fraud.
Its market capitalisation has collapsed from more than USD 90 billion in the summer of 2015 to a current value of USD 5.2 billion.