Researchers from The University of Queensland, the University of New South Wales and Flinders University of South Australia found that some lifestyle behaviours are linked to negative brain functions in women.
The eight-year study involved 489 middle-aged and older women from Brisbane who were recruited from 2001.
Professor Gerard Byrne from the UQ School of Medicine and Professor Nancy Pachana from the UQ School of Psychology led the study.
Pachana said the effect these lifestyle factors could have on cognitive performance occurred much earlier than expected.
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She said objective thinking and memory tests were administered on three occasions over eight years and each time results showed smoking appeared to have impaired cognitive function.
"Moderate drinking and high physical activity levels offered protective effects over time, compared to not drinking and low levels of physical activity," Pachana said.
"Effects remained for light to moderate drinkers even after adjusting for physical activity levels.
"Current smokers performed worse than past smokers, who in turn performed worse than those who had never smoked," Pachana said.
If the women in the study engaged in increasing intensities of physical exercise, rather than just quantity of physical activity, they were less likely to experience declines in thinking, researchers said.