The 43-year-old rapper will appear on episode 11 of the series, which will air next month or early March, reported Digital Spy.
The drama stars Terrence Howard as ruthless music executive Lucious Lyon and Taraji P Henson as his ex-jailbird wife.
Naomi Campbell, Courtney Love and Gabourey Sidibe also have recurring roles.
Dogg is also working on his new album Bush, which is his first studio record for Columbia Records. Bush is due for release this spring and will be produced by Pharrell Williams.